Ciencias de la Salud

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    INFLUENCIA DE LOS CARBO HIDRATOS SIMPLES EN LA PRESENCIA DEL CÁNCER: ARTÍCULO DE REVISIÓ N BIBLIOGRÁFICA
    (2025-06-18) Rojas Fernández, Andrea Alejandra; Hidalgo Morales, Kattyta Patricia; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Nutrición y Dietética
    The W arburg effect accelerates th e obtaining of en ergy by an aero bic glycolysis, therefore th ere is an increase in th e gro wth and proliferation of tumor cells, much of si mple carbohydrates inhibit th e positive effects in th e treatment of the oncological. It is esti mated th at by 2050 it will increase exponen tially to 35 million cancer p ati ents. Wi th preval ence in men of th e cervix of moth er and in men of prostate and bladder. This co mpreh ensive systematic revi ew is carri ed o ut in databases such as PubMed, Sci ELO, ProQuest, Mend eley, Di alnet, Google Scholar, and Research Gat e. With keywords such as: Diet -Carbohydrate s; Cancer; Hyperglycemia ; Simple Carbohydra tes, Glucose; fructose and Nutriti o n -Cancer. Nutrition and cancer, hyp erglycemi a. In ord er to know th e participati o n of carbohydrate metabolism in th e presence of cancer. Carbohydrates are important in th e h ealthy diet, as it is th e main so urce o f energy, and will d ep end on th e form of absorption (fast, slo w or resistan t); ho wever, nowad ays, it is important to use it. Excessive consump tion o f simpl e, refin ed sug ars and low quality carbohydrates with emp ty calories are booming, being an i mportant factor in the physiological alteration that influence the incidence o f physical and mental pathologies, including the various types of cáncer.
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    CARGA EXOSOMAL: BIOMARCADORES EN EL DIAGNÓSTICO DEL CÁNCER
    (2025-02-25) Campoverde Ortega, Gabriela Noemi; Proaño Pérez, María Elizabeth; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    Cancer is a global health problem, and one of its main challenges is timely detection. Therefore, the determination of exosomal biomarkers has been proposed as a possible tool when diagnosing this pathology. In addition to being important elements in intracellular communication by transporting cellular biomolecules such as lipids, nucleic acids, proteins, and metabolites associated with their producer cell, they act as main regulators of the tumor microenvironment, responsible for angiogenesis, progression, and development of metastasis. For their isolation, there are various techniques related to ultracentrifugation, ultrafiltration, and immunoaffinity that allow their separation from different sources, whether biological fluids or culture media, facilitating their study in the context of cancer.
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    EXPERIENCIA DE VIDA DE UNA ESTUDIANTE DE ENFERMERÍA CON CÁNCER
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Enfermería, 2024-10-04) Ruiz Quinapanta, Allison Daniela; Pachucho Flores, Ana Pamela
    Cancer is a pathology that can originate in almost any organ or tissue of the body, all cancers, has the same underlying basis: cells out of control which accumulate forming tumors, but there is another variant of the disease in which tumors are not necessarily formed despite the uncontrolled multiplication of cells in the blood, as in the case of leukemia. Objective: To relate the life experience of a nursing student with cancer; (2) Methods: This study has a qualitative approach, case study design and descriptive scope, through the narration of experiences and perceptions of a nursing student with cancer during her educational process. The technique used is a semi-structured interview, prior to the application of an informed consent, once the information was collected it was recorded and transcribed in order not to lose any important information; (3) Results: This inspiring story highlights the importance of mutual support and empathy in times of adversity; (4) Conclusions: it was possible to demonstrate that, through unwavering determination, courage and perseverance, the power of caring and compassion are fundamental axes in the recovery of health, which affects not only patients but also those who care for them.
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    ANTIOXIDANTES EN LA PREVENCIÓN Y TRATAMIENTO DE CÁNCER
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Nutrición y Dietética, 2024-09-25) Navas Bassante, Camila Anahys; Viteri Robayo, Carmen Patricia
    Cancer is considered the leading cause of death worldwide with 10 million deaths annually, the most prevalent are breast and lung cancer, and the main risk factors are overweight, smoking, sedentary lifestyle and a diet with low consumption of fruits and vegetables rich in antioxidants, Therefore, this review article has the objective of identifying the influence and relationship of the consumption of antioxidants in the prevention and treatment of cancer. For this purpose, a bibliographic review of the last 5 years was carried out in scientific databases such as Google Scholar, Scielo, PubMed, Elsevier, Web of Science. The languages used were Spanish, English and Portuguese, as a result it was obtained that oxidative stress damages DNA, which generates a process of carcinogenesis, and antioxidants have the ability to prevent oxidative stress by stabilizing free radicals, so it was concluded that antioxidants can prevent cancer if consumed from natural sources, however in their treatment there are divided opinions, so more research should be conducted in depth on the subject.
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    TIPOS DE DIETA EN LA COMPOSICIÓN DE LA MICROBIOTA INTESTINAL Y SU RELACIÓN CON EL CÁNCER
    (Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Nutrición y Dietética, 2024-09-20) Cerruffo Acosta, Brigitte Alexandra; Hidalgo Morales, Kattyta Patricia
    This article was carried out with the aim of making known the various diets that favor the composition of the intestinal microbiota and its relationship with cancer through the review of several investigations related to the subject, based on the above this work allows to reinforce the importance of having a proper diet for the correct functionality of the intestinal microbiota, since this would be both a preventive and therapeutic strategy for many diseases such as cancer and the benefits that would also bring the use of probiotics and prebiotics among others, which would be of great importance to contribute to a healthier microbiota, becoming a key factor, as a mediator of the effects of diet on health and source of Inter variability of response to a diet. Finally, some examples of dietary intervention in which the microbiota has been shown to play a key role in the results obtained are named. Therefore, it is of utmost importance to increase the knowledge about the etiological role of the microbiota in the development of a disease such as cancer and its knowledge could be of great utility and a fundamental tool in the detection and treatment of this disease, as well as to carry out a timely and individualized evaluation and intervention, with a multidimensional, systemic, multi and interdisciplinary approach.
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    APLICACIÓN DE LA PROTEÓMICA EN EL DIAGNÓSTICO DE CÁNCER DE MAMA: AVANCES Y LIMITACIONES
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-13) Condo Paredes, Katheryn Nathaly; Ron Mora, Álvaro Sebastián
    Introduction. Breast cancer is an extremely complex and heterogeneous disease that is characterized by uncontrolled growth of cells belonging to the breast tissue. It is essential to identify more sensitive biomarkers. A recent response has been the use of proteomics technology, which has provided excellent help in the characterization of new molecular biomarkers by measuring protein profiles. Objetive. Analyze the application of proteomics in the diagnosis of breast cancer, its Advances and Limitations. Methodology. To prepare the article, a bibliographic review was used based on research in highly relevant scientific journals, repositories and health databases such as Scopus, Embase, Science Direct, ProQuest, PubMed, Scielo, Medline. Results. The reviewed documents provide information about the application of different proteomic techniques in the diagnosis of breast cancer, many of their advances, but also the limitations that arise throughout this study. Many of the laboratory tests that can be performed for the diagnosis and management of breast cancer are highlighted. Conclusion. The application of proteomics in the diagnosis of breast cancer has represented a promising advance towards the early and personalized detection of this disease.
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    NUEVOS BIOMARCADORES URINARIOS EN EL DIAGNÓSTICO Y MONITORIZACIÓN DEL CÁNCER
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-13) Criollo Guambo, Joselyn Pamela; Cevallos Bonilla, Victoria Maritza
    Cancer is a global concern, and its early detection is crucial. This article explores the role of urinary biomarkers in cancer diagnosis and follow-up. It highlights that urine, containing a variety of analytes, has become a valuable tool for cancer detection. Several specific biomarkers for different types of cancer are discussed, such as PCA3 for prostat e cancer, NMP22 and BTA for bladder cancer, and microRNA and proteins for breast and lung cancer. The importance of these biomarkers in clinical practice is emphasized, as they allow faster diagnoses, more accurate treatments, and effective disease monitori ng . Urinary biomarkers are critical to improve early detection and managem ent of cancer , potentially improving clinical outcomes and quality of life for patients.
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    USO DEL CANNABIS MEDICINAL EN ELALIVIO DEL DOLOR
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Enfermería, 2024-05-28) Cunalata Castro, Stefania Aracely; Guarate Coronado, Yeisy Cristina
    Introduction: The use of cannabis has been a rather controversial issue, starting from its legalization in some countries, the way in which it is consumed either for the benefit of health or recreationally, currently its medicinal use is on the rise due to the fact that analgesic drugs are unfavorable in patients suffering from chronic pain, which has made cannabis an alternative means of pain relief. Methodology: Obtaining the information was based on the PRISMA diagram for the initial search of scientific articles in databases such as: Scopus, PubMed and Google Scholar, using the search equation "medicinal cannabis AND pain". The selection of scientific documents was made using the following inclusion criteria: Articles that were original or systematic review, that the title of the document contains the terms cannabis, pain, health, alternative treatment, pain relief, free access articles in English and Spanish, published between 2018 and 2023. Incomplete documents or whose methodology was not consistent with the subject of the study were excluded. Results: 54 articles were found which allowed to know the benefits that the use of cannabis represents in pain relief.
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    ATENCIÓN DE ENFERMERÍA EN PACIENTES ONCOLÓGICOS CON CUIDADOS PALIATIVOS
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Enfermería, 2024-05-28) Cañaveral Estrella, Nieves Liseth; López Pérez, Grace Pamela
    Introduction: Cancer continues to be a problem in health care, especially in cancer patients with terminal diagnoses, the execution of palliative care is aimed at improving the quality of life by providing a dignified death. Objective: Describe nursing care in cancer patients with palliative care. Methodology: Systematic review in selected studies or investigations through the application of the PRISMA method. Results: Selection and analysis of 16 original and review articles that meet the selection criteria under reliable supports. Discussion: The number of selected articles supports the importance of nursing care in cancer patients, describes the symptoms present regardless of the type of cancer the patient presents, and also explains the degree of patient satisfaction with the interventions carried out. by nursing. Conclusions: Palliative care has become a fundamental point in the care of patients with oncological diseases, nursing has a fundamental role where their care is focused on physical, psychological and emotional well-being to offer comfort to both the patient and their family until the end of the day. end of life Palliative care focuses on the integrality of the patient's quality of life.
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    Relación del estado nutricional y la calidad de dieta de los pacientes adultos con diagnóstico de cáncer
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Nutrición y Dietética, 2023-09-01) Guaygua Arroyo, Leidy Jazmin; Chávez Velasco, Irlanda del Lourdes Dra.
    The purpose of this research project was to determine the nutritional status and diet quality of patients diagnosed with cancer in a private health entity in the city of Ambato. The study was descriptive, cross-sectional, and the subjects included in the study were 45 patients, 31 were female and 14 were male. For the assessment, a nutritional evaluation instrument of our own authorship was used, which arose from the compilation of different subjective assessment instruments previously used in other studies. In this nutritional status assessment tool, anthropometric indicators such as weight, height, BMI, fat mass and muscle mass were taken into account. Biochemical indicators considered were hemoglobin, hematocrit, lymphocytes and albumin. Regarding the clinical assessment, the main symptoms that appear in the disease were taken into account and finally, to determine the quality of the diet, a 24- hour recall was used, with a sampling and analysis of exact grams per food with the help of the Photographic Manual of Ecuadorian Foods. The results of the research were processed with the Pearson Chi-square statistical test for the crossover of variables, which showed that according to the indicators used, it can be considered that there is a significant relationship between nutritional status and the quality of the diet of cancer patients.