Maestría en Laboratorio Clínico Mención Microbiología Clínica

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    PERFIL DE RESISTENCIA ANTIMICROBIANA EN MUJERES EMBARAZADAS CON INFECCIÓN URINARIA QUE ACUDAN AL HOSPITAL BÁSICO SAN MARCOS
    (Universidad Técnica de Ambato / Facultad de Ciencias de la Salud / Centro de posgrados, 2024-09-03) Coello Barahona, Glenda Patricia; Chicaiza Tayupanta, Jesús
    The proliferation of pathogenic microorganisms in the urinary tract is a distinctive feature of urinary tract infection in pregnant women. Physiological changes linked to pregnancy increase the likelihood of complications that can have a significant impact on both the mother and the fetus. The present research aimed to characterize the antimicrobial resistance profile in pregnant women with urinary tract infection who attend the San Marcos Basic Hospital. The study had a mixed approach, observational and descriptive, integrating qualitative elements accompanied by a bibliographic review of digital repositories, books, scientific articles, journals, websites, among others; and quantitative that allowed the recording of the results of the urine cultures of the 100 pregnant women who attended the San Marcos Basic Hospital during the period August 2023 - January 2024. Regarding the results, the following findings were reported: the main causal agent of urinary tract infections was the Escherichia coli bacteria. (65%), followed by Escherichia coli ESBL productive strain (9%), Klebsiella aerogenes (7%), Proteus Mirabilis (7%), and Enterobacter cloacae (3%). The antimicrobial resistance patterns for E. coli were Ampicillin and Sulfamethoxazole/trimethoprim (70%), Escherichia coli. ESBL, with resistance to Ampicillin, Cefuroxime, Sulfamethoxazole/trimethoprim, Ampicillin/sulbactam, Ceftazidime, and Amoxicillin/clavulanic acid (80%); for Klebsiella Pneumoniae it presented resistance to Ampicillin (84%) and Gentamicin (67%); Proteus Mirabilis had resistance to Amikacin and Cefuroxime (50%), and resistance to Ampicillin and Sulfamethoxazole/trimethoprim with 90%. Finally, resistance to Enterobacter Cloacae was Ampicillin and Norfoflaxin Ceftazidime (100%) and Cefuroxime and Clarithromycin (50%). The study concludes that, in the San Marcos Basic Hospital, an adequate use of antibiotics should be carried out, in addition to evaluating the use of antibiotics in pregnant patients who present a urinary tract infection; and how the medical staff requires information related to sensitivity and resistance, so that this can be permanently socialized.