PRUEBAS HEMOSTÁSICAS EN PACIENTES CON DIABETES MELLITUS TIPO 2

Abstract

Introduction: Type 2 Diabetes Mellitus (DM2), or non-insulin-dependent, is a chronic disease characterized by insulin resistance or reduced insulin levels, which in turn contribute to high glucose levels. This condition, together with the associated chronic inflammation, generates several complications, one of them is an imbalance in the hemostatic system. Objective: To identify laboratory hemostatic tests and their clinical usefulness in patients with type 2 Diabetes Mellitus. Methods: A bibliographic review was carried out in various databases of interest, including articles published in the last 5 years, in addition to those articles published before 2019 that limited relevant information on the topic. Development: Original articles that analyzed hemostatic tests in patients with DM2 were reviewed and it was established that the main tests that are altered are TTP, MPV, fibrinogen, PAI-1, VWF and DD, since they have presented consistent results in different research. Conclusions: It is necessary to perform hemostatic tests in patients with DM2, since it has been seen that untreated patients may present thrombotic disorders that, in the long term, can generate cardiovascular alterations.