Implementación de un sistema de vigilancia de resistencia antimicrobiana en el Hospital SOLCA Núcleo de Tungurahua

Abstract

Bacterial resistance is a public health problem that afflicts, at a global level, different health houses. Microorganisms resistant to most antimicrobials are known as ultra-resistant. The phenomenon is very worrying because infections by resistant microorganisms can cause the death of the patient, be transmitted to other people and generate great costs for both patients and health homes. The objective is to implement an antimicrobial resistance surveillance system that includes developing and applying microbiological sampling protocols and the detection of extended-spectrum betalactamase (ESBL) and carbapenemase-producing strains. Gram staining and the BBL Crystal ID identification system will be used for the bacterial identification. In addition, for the identification of ESBL, the combined disk diffusion method of ceftazidime/ceftazidime + clavulanic acid and cefotaxime/cefotazime+claculanic acid will be used, and for the carbapenemases detection, the EDTA, boronic acid, mCIM and eCIM tests will be performed, according to the CLSI guidelines, to generate information on the changes in the antimicrobial resistance pattern of the microorganisms subject to it, in order to improve the microbiology area of the SOLCA Núcleo de Tungurahua Hospital.