Ciencias Agropecuarias

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Author: search.filters.author.Flores Jácome, Alexandra MelissaSubject: search.filters.subject.CANINOS (Canis lupus familiaris)

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    Medición seriada de los niveles de lactato como marcador de la respuesta terapéutica y mortalidad en caninos (Canis lupus familiaris) con cuadros de parvovirus
    (2024-02) Flores Jácome, Alexandra Melissa; Lozada Salcedo, Euclides Efraín
    The following research had as main objective to determine the existing relation between the measurement in series of the lactate levels and a series of variable aspects like; therapeutic answer, mortality, and hemodynamic variables in canines (Canis lupus familiaris) with parvovirus appearance. The serial measurement of the variables was established according the hours (T0, T6, T12, T24, T48, y T72). The research was applied in the Vet Clinic Urban Pet, with the participation of 17 canines diagnosed with canine parvovirus type 2 (CPV-2) due to an inmunochromatographic examination. The registers for lactate and hemodynamic variables (heart rate, blood pressure, pulse oximetry, capnography, and pulse pressure) were taken before the treatment setting and hospitalization for the values (T0). The same values were taken again for the next hours. The results were observed in a statistic way through an analysis of chi-square in order to relate the blood lactate levels with the mortality, having as a statistic and meaningful result (p<0,0001). According to the relation as a prognostic from the therapeutic answer through the lactate clearing respect to the time, meaningful relations were stablished for the (T12) and (T24) depending on the analysis about behavior bends of the surviving ones versus the non-surviving ones. Finally, for the hemodynamic variables, a variance analysis was used, the ones that presented significance (p<0,05) respect to lactate blood values were: heart rate (p:0,009), systolic blood pressure (p:0,0478), diastolic blood pressure (p:0,0096), pulse oxytometry (p:0,0215), and pulse pressure (p:0009); on the other hand, the ones that didn’t have a meaningful result (p>0,05), were the variables about capnography (0,0819) and medium blood pressure (p:0,7395). Keywords: lactate, serial levels, parvovirus, times prognosis, surviving, nonsurviving