Ciencias de la Salud

Permanent URI for this communityhttp://repositorio.uta.edu.ec/handle/123456789/813

Browse

Filters

2023 - 20242

Settings

Subject: search.filters.subject.SÍNDROME DE TURNER

Search Results

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    TRATAMIENTO DE REEMPLAZO HORMONAL ENFOCADO EN LAS OPCIONES DE FERTILIDAD EN MUJERES CON SÍNDROME DE TURNER
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2024-09-26) Garcia Nuñez, Marcos Andrés; Cruz Castillo, Yessenia Magaly
    Introduction: Hormone replacement therapy in women with Turner Syndrome, focusing on estrogen, progesterone, and gonadotropins such as FSH and LH, is critical for addressing infertility associated with this genetic condition. This study reviews existing literature to assess the efficacy of these drugs in improving ovarian function and fertility options. Objective: To analyze and synthesize current literature on hormone replacement treatment options and their effectiveness in enhancing fertility in women with TS. Methodology: A literature review was conducted on medical platforms such as PubMed and MEDLINE, using keywords such as "Turner Syndrome", "Hormone Replacement Therapy", and "Fertility". Studies from the last 5 years, in both English and Spanish, focused on hormonal treatments and fertility, were included. Results: Reviewed studies indicate that drugs like estrogen and progesterone in hormone replacement therapy can improve ovarian function in women with TS. Some cases reported success using FSH and LH to stimulate ovulation. However, variability in responses and potential side effects require careful consideration. Conclusions: Treatment with estrogen, progesterone, FSH, and LH offers possibilities for fertility improvement in TS, but must be personalized and rigorously monitored to optimize outcomes and minimize risks.
  • No Thumbnail Available
    Item
    Metabolismo de la glucosa en el síndrome de turner
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2023-03-01) Pacheco Bonilla, Alisson Gisselle; Guangasig Toapanta, Víctor Hernán Bq.F. Mg.
    Turner syndrome is one of the most frequent chromosomal disorders, caused by the partial or total loss of one of the sex chromosomes, adult patients have a high prevalence of diabetes mellitus, and the altered glucose metabolism in this population seems to be genetically triggered. In adults affected by TS, abnormal glucose metabolism is found in >70% of this population. We seek to achieve early diagnosis in patients with Turner syndrome without type 2 DM by identifying clinical and biochemical risk factors before cardiometabolic risk and thus micro- and macrovascular complications increase. We comprehensively reviewed the available evidence related to the influence of insulin secretion and sensitivity, obesity, autoimmunity, growth hormone, and sex hormone replacement therapy on the onset of DM in these patients. The results of the present study would allow us to identify the importance of laboratory tests in patients with Turner syndrome for the diagnosis of metabolic syndrome, insulin resistance, and therefore the development of Diabetes mellitus and to implement therapeutic options promptly to improve or lengthen the temporality of onset of complications.