Ciencias de la Salud
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Item “Determinación de colinesterasa eritrocitaria en mujeres de edad fértil y embarazadas expuestas a plaguicidas”(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Laboratorio Clínico, 2017-10-01) Cañar Robalino, Adriana Carolina; Bqf. Tinajero Vásquez, María FernandaThe increasing use of organophosphate insecticides in agriculture and in the interior of homes and schools poses a potential risk to health. As the use of these agents increases, acute and chronic exposure has become more common. Exposure of pregnant women to organophosphates is an important clinical entity due to its effects on two organisms; the mother and the fetus. The objective of this study was to determine erythrocyte cholinesterase levels in women of childbearing age and pregnant women who had exposure to pesticides. It was a descriptive study, which evaluated women of childbearing age and pregnant women who exhibit exposure to organophosphates. Among the group of women of childbearing age we can find that barely e1 0% presents low values without having exposure to pesticides, whereas 29.4% of pregnant women without pesticide exposure have presented low levels, despite the exposure in women of childbearing age 24.3% had adequate levels of erythrocyte cholinesterase only 3 out of 10 women of childbearing age with or without pregnancy and who had exposure to pesticides had low levels, it should be noted that the reference levels for pregnant women are lower compared to non-pregnant women. This study gives evidence of a drop in serum cholinesterase concentration in pregnant women. The influence of decreased cholinesterase in pregnancy may have been disproportionately greater in some women who have been exposed to a pesticide than other women in fertile age exposed and unexposed.Item “Determinación de gama GT y colinesterasa y su relación como marcadores de recaída en alcohólicos”(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Laboratorio Clínico, 2017-04-01) Silva Flores, Nancy Fernanda; Bqf. Ramos Ramírez, Martha Cecilia Mg.The purpose of this research project was to carry out chemical analysis, mainly the determination of the concentrations of the enzymes Gamma GT and serum Cholinesterase in anonymous alcoholic patients of the Guild of Tungurahua, through a set of activities that included visiting the patients of the Center of Recovery, applying surveys to know more about their quality of life, risk factors and what diseases can carry this substance in the liver, through laboratory tests. In this study a qualitative and quantitative approach was used, since it was in contact with the anonymous alcoholic patients of the Guild of Tungurahua giving a clear and concise perspective to give to understand the development of the investigation and by the laboratory tests that will take finished. All data from the survey and the results of the laboratory tests obtained were taken in numbers and percentages that appear as graphs. The importance of evaluating the enzymes Gamma GT and Cholinesterase in alcoholic patients constitutes a fundamental pillar within a medical assessment to rule out or confirm an alteration of the concentration of the enzymes that are usually markers of liver damage. In conclusion, it was determined that all the anonymous alcoholic patients of the Guild of Tungurahua performed the laboratory tests as GT Range and Cholinesterase; Which exceeded the normal reference values; Since they were not within the normal range; In general the patients studied have several factors that have influenced the development of the disease, such as the time of consumption, the onset of addiction, time of exposure, social, personal and socioeconomic problems that led to an addiction.Item Factores laborales asociados a la Intoxicación crónica por inhibidores de la Colinesterasa en trabajadores agrícolas de San Vicente, Cantón Quero 2015-2016(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Dirección de Posgrado, 2016-11-01) Robalino Travez, Teresa LilianaMd.; Sunta Ruiz Dr. Esp, Mario LeopoldoIntroduction: A global pesticide use has increased, which implies a risk for the working population, but unfortunately did not use the correct protective equipment that relates for lack of knowledge, so that there is direct exposure. So the World Health Organization estimates that worldwide more than 750,000 people would present some kind of chronic effect by being in contact with pesticides Objective: To identify factors related to occupational chronic exposure to cholinesterase inhibitors in farm workers, San Vicente, Quero 2015-2016. Methodology: an observational, descriptive, cross-sectional study presents the universe of study constituted 200 farm workers took a sample of 97 but only 78 met the inclusion criteria. Results: It was noted that there is a misuse of pesticides by lack of information and training in 67% of agricultural workers. Protective equipment used boots were 100%, 20.5% mask and gloves 3.8%. In addition low levels of erythrocyte cholinesterase was identified in 84.4% of men and 39.9% in women, exposure time in years and the frequency of use is directly proportional; therefore the longer and more often exposed percent have low values. By analyzing neurological, neuropsychological and cognitive disorders, both men and women had involvement at all scale