Ciencias de la Salud
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Item Complicaciones tromboembólicas en pacientes con infección por covid 19. Revisión narrativa.(Universidad Técnica de Ambato/Facultad de Ciencias de la Salud/Carrera de Medicina., 2022-10-24) Moyolema Moyolema, Vanessa Abigail; Pinos Cedeño, María JoséThe disease generated by the outbreak of coronavirus type 2 in 2019 called COVID-19 led the world to a health crisis after the consequent appearance of a pandemic that affected all social strata. Infection by this virus caused millions of deaths from its pathophysiology, which is characterized by the presence of respiratory symptoms. However, the disease generates an inflammatory effect with subsequent elevation of cytokines, causing a cascade of situations that contribute to the development of thromboembolic events, in addition, risk factors are associated that increase the mortality rate such as obesity, diabetes mellitus, arterial hypertension, age over 60 years, also having an increased probability of developing a more complex clinical picture and complications such as coagulation disorders. This article seeks to consolidate relevant and current information based on research and analysis of international and high-impact literature on the clinical picture that a patient with Covid 19 infection who develops thromboembolic complications may present.Item “Hemofilia tipo A”(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Medicina, 2018-06-01) Guerrero Casquete, César Andrés; Mejía Ortiz, Ruth Aurelia Dra.Hemophilia is a devastating disease of genetic origin, recessive and linked to the X chromosome, which contains the genes that code for the hemostatic factors VIII and IX. Some specific mutations of these genes cause the appearance of hemophilia A or B. Hemophilia type A is caused by the reduction in the amount or activity of coagulation factor VIII, a failure at this point of the cascade of coagulation. The result is poor fibrin formation, which causes the coagulation to be much longer and the coagulum more unstable. Approximately 1 in every 5000 males is affected. The severity of the clinic correlates with factor levels. The following clinical case analysis is a 4-year-old male patient with a personal pathological head trauma of mild cranial encephalic trauma at 2 years and a personal surgical history of wound cauterization at the level of the lip when he was 2 years 6 months, that presents approximately 3 days of gingivorrhagia evolution after molar extraction, also refers to asthenia, anorexia, marked weakness and generalized pallor, to the physical examination he was: pale skin, at the level of the gingiva, there is an injury in the process of healing, no stigmas or active bleeding on admission, auscultation presents: tachycardia, rhythm regular, normofoneticos heart sounds, ausculta murmur at the level of holosistolico tricuspid focus, has hemoglobin 5.9 g/dl, hematocrit 20.1 %. He´s admitted to the pediatric hospitalization service of Hopital IESS Ambato where complementary tests are performed showing altered values of part time of thromboplastin what leads to perform other complementary tests to arrive the diagnosis of hemophilia type A