Ciencias de la Salud

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    Relación triglicéridos/colesterol HDL: el papel del laboratorio como indicador de insulinorresistencia
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-03-05) Solís Salinas, Kevin Alexis; Galárraga Pérez, Edison Arturo
    Introduction. Insulin resistance or insulin resistance (IR) is defined by the reduction in the processes of insulin uptake, to stimulate the use of glucose in different tissues and to eliminate the production and output of hepatic glucose. On the other hand, currently there are different standard methods to evaluate IR, but these types of methods are highly expensive and their processing requires time. Objective. The objective of the literature review was to analyze the triglyceride/HDL cholesterol ratio and the role of the laboratory as an indicator of insulin resistance. Methods. To carry out the bibliographic review article, a documentary exploration method was used through a search for information in databases of journals such as Google Scholar, Pubmed, Scopus, Elsevier, SciELO and Medline. Results. The articles analyzed provide relevant information on the TG/HDL-C ratio and the importance of the laboratory as an indicator to predict and evaluate insulin resistance. Relevant information was also found on dyslipidemias and the different methods used for evaluation of the IR. Conclusion. The triglycerides/HDL-C ratio is of utmost importance in the early diagnosis of insulin resistance, since in the studies reviewed a high value of this ratio is consistent with IR.
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    Relación triglicéridos/colesterol HDL: el papel del laboratorio como indicador de insulinorresistencia
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-03-01) Solís Salinas, Kevin Alexis; Galárraga Pérez, Edison Arturo
    Introduction. Insulin resistance or insulin resistance (IR) is defined by the reduction in the processes of insulin uptake, to stimulate the use of glucose in different tissues and to eliminate the production and output of hepatic glucose. On the other hand, currently there are different standard methods to evaluate IR, but these types of methods are highly expensive and their processing requires time. Objective. The objective of the literature review was to analyze the triglyceride/HDL cholesterol ratio and the role of the laboratory as an indicator of insulin resistance. Methods. To carry out the bibliographic review article, a documentary exploration method was used through a search for information in databases of journals such as Google Scholar, Pubmed, Scopus, Elsevier, SciELO and Medline. Results. The articles analyzed provide relevant information on the TG/HDL-C ratio and the importance of the laboratory as an indicator to predict and evaluate insulin resistance. Relevant information was also found on dyslipidemias and the different methods used for evaluation of the IR. Conclusion. The triglycerides/HDL-C ratio is of utmost importance in the early diagnosis of insulin resistance, since in the studies reviewed a high value of this ratio is consistent with IR.
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    Diabetes mellitus en pacientes adolescentes
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2023-10-04) Escobar Quisaguano, Jomayra Vanessa; Ruth Aurelia, Mejía Ortiz
    Diabetes is a chronic disease that affects thousands of adolescents worldwide, and its prevalence has been increasing in recent decades. It is characterized by elevated blood glucose levels due to a lack of insulin production or poor insulin utilization. While diabetes can manifest itself at any stage of life, its presence in adolescence poses additional challenges due to the physical and emotional changes inherent to this stage of development. There are several types of diabetes, the most common in adolescence being type 1 diabetes, type 2 diabetes and type MODY diabetes. Type 1 diabetes in adolescents is due to a lack of insulin due to the destruction of insulin-producing cells, while type 2 diabetes is associated with insulin resistance and is often linked to lifestyle factors such as obesity. The main symptoms are polyphagia, polyuria, nocturia, weight loss with increased appetite, fatigue and weakness. A good clinical history and tests such as blood glucose, glycosylated hemoglobin, investigation of autoantibodies and anti-C-peptide antibodies are important for the diagnosis. In the treatment it is important the intervention of a multidisciplinary team involving the physician, nutritionist, psychologist and family members. The aim of treatment is to improve the quality of life and reduce long-term complications in adolescents.