Medicina
Permanent URI for this collectionhttp://repositorio.uta.edu.ec/handle/123456789/815
Browse
3 results
Search Results
Item “Hemofilia tipo A”(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Medicina, 2018-06-01) Guerrero Casquete, César Andrés; Mejía Ortiz, Ruth Aurelia Dra.Hemophilia is a devastating disease of genetic origin, recessive and linked to the X chromosome, which contains the genes that code for the hemostatic factors VIII and IX. Some specific mutations of these genes cause the appearance of hemophilia A or B. Hemophilia type A is caused by the reduction in the amount or activity of coagulation factor VIII, a failure at this point of the cascade of coagulation. The result is poor fibrin formation, which causes the coagulation to be much longer and the coagulum more unstable. Approximately 1 in every 5000 males is affected. The severity of the clinic correlates with factor levels. The following clinical case analysis is a 4-year-old male patient with a personal pathological head trauma of mild cranial encephalic trauma at 2 years and a personal surgical history of wound cauterization at the level of the lip when he was 2 years 6 months, that presents approximately 3 days of gingivorrhagia evolution after molar extraction, also refers to asthenia, anorexia, marked weakness and generalized pallor, to the physical examination he was: pale skin, at the level of the gingiva, there is an injury in the process of healing, no stigmas or active bleeding on admission, auscultation presents: tachycardia, rhythm regular, normofoneticos heart sounds, ausculta murmur at the level of holosistolico tricuspid focus, has hemoglobin 5.9 g/dl, hematocrit 20.1 %. He´s admitted to the pediatric hospitalization service of Hopital IESS Ambato where complementary tests are performed showing altered values of part time of thromboplastin what leads to perform other complementary tests to arrive the diagnosis of hemophilia type AItem “Estudio de factores que influyen la adherencia al tratamiento de anemia ferropenica en niños de 6 a 24 meses atendidos en el Subcentro de Salud de Cevallos”(2014-11-01) Barreno Vargas, Verónica Maricela; Chacón Pinto, María de Lourdes Dra. MSc.This research work was to question the determining factors that influence adherence to treatment of anemia in children aged 6-24 months seen in the health Subcentre Cevallos during the period January June 2012 a sample of 48 patients was taken and caregivers established that ignorance of caregivers about the disease consequences and therapeutic scheme seen in more than half of the study population. With regard to the drug was observed that all children who received the treatment had side effects being the most observed constipation, difficulty also seen to take the medicine in more than half of patients consequently resulting in discontinuation of treatment in about all of these, showing poor adhesion. More than half of patients are under the care of grandparents, with mostly basic education, a significant proportion QQDD made with agricultural activities, all these factors have a negative impact on adherence, as there are difficulties in understanding and understanding the signs of the health professional. In researching the information given by the health system found that less than half of caregivers received information about the disease, and almost all patients know the duration of treatment, showing a lack of understanding, for the information provided by the doctor should be looking to achieve clearly better grip. The observed lack of adherence to treatment in the majority of the population implying failure in the administration of ferrous sulfate, forgetting to administer the medication, non-compliance with dietary recommendations and inadequate monitoring of the disease.Item Anemia Megaloblástica(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Medicina, 2016-09-01) Freire Montesdeoca, Juan Gabriel; Naranjo Perugachi, Jeaneth del Carmen Dra.This research aims to determine the cause of megaloblastic anemia, which depends on the treatment promoting studies to generate scientific evidence involved in the management of deficiency of vitamin B12 and folic acid and the resulting megaloblastic anemia. The most common causes of metabolic disorders megaloblastosis are vitamin B12 and folate (maturation factors). These involved in the transport of methyl, essential for cell proliferation and division. For this purpose in the current analysis, a clinical case of a male patient 63 years old with a history of Type 2 diabetes mellitus more hypertension patient attended the Emergency Teaching Hospital Ambato to present three weeks ago generalized fatigue with dizziness occurs , but paresthesia in lower limbs. On physical examination generalized paleness. Where it is entered and evaluated with laboratory tests meeting: HGB: 5.7 g / dL HCT: 17.1% MCV: 125.4 fl, MCH 41.9 pg, MCHC: 33.4 g / dl, PLT 87000 u / L. Urea in blood chemistry: 58.6 mg / dL, glucose 350.6 mg / dL, CREATININE 1.40 mg / dL. Where it is valued by deciding to transfuse Nephrology 3 packs Globular more treatment and Hematology orders who decide to perform additional tests quantification of Vitamin B12 + Folic acid and iron profile meeting ferritin 1753 mg / dL. A stable once the patient is discharged waiting for tests and bone marrow puncture, but for outpatient follow-up will be decided. It is not possible to establish behavioral changes regarding risk factors and progression, so that the neglect of both the patient, family, and poor monitoring and control by primary care, allowing the disease to progress. For this case the pattern of research should be tailored to each patient, giving importance to the clinical presentation. In laboratory settings with limited facilities, a therapeutic trial of vitamin B12 or folic acid is useful to determine the specific vitamin deficient megaloblastic anemia. During the analysis we can infer that both folate and vitamin B12 are essential to the human body components, so the lack of these nutrients can cause not only anemia but also alterations at the cellular level, which will reveal to the range of clinical manifestations present. In turn, the deficit thereof, constitutes a risk factor for cardiovascular, oncological diseases and pregnant women cause neonatal pathologies. At the end of the improvement opportunities, to the author, can be important and desirable to improve the management and the recording of individuals with these diseases are discussed.