Importancia de la terapia de bacteriófagos en infecciones bacterianas multirresistentes

Abstract

The growing danger posed by multidrug-resistant bacteria has profoundly hampered the effectiveness of conventional antibiotics, underscoring the urgent need for alternative therapeutic options. Phage therapy, defined by the application of viruses that attack specific bacteria, has been revitalized as a strategy of choice in this regard. The aim of the research is to examine the importance of bacteriophage therapy as an alternative for the treatment of multidrug-resistant infections. A literature review of the literature on clinical and experimental studies focused on the efficacy of bacteriophages against multidrug-resistant bacterial infections was conducted. The studies reviewed showed that phage therapy is highly specific in multidrug-resistant bacteria, unlike traditional therapies. Clinical studies show therapeutic success in infections considered multidrug-resistant, particularly in Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus (MRSA). The impact of bacteriophage therapy is a complement to conventional antibiotics, so this therapy should be considered as an alternative in the treatment of multidrugresistant infections.