EFICACIA TERAPÉUTICA DE LOS ANESTÉSICOS DISOCIATIVOS EN DEPRESIÓN

Abstract

Introduction: Depression is a prevalent mental disorder that significantly affects the quality of life despite the existence of conventional treatments, a large proportion of patients do not respond adequately to these, the use of dissociative drugs for the treatment of depression has gained attention. in recent years, especially with the use of ketamine. This anesthetic has been used clinically for decades and has demonstrated rapid and significant antidepressant properties, especially in patients with resistant depression. Methods: This is a review of the literature that analyzes the therapeutic efficacy of dissociative anesthetics, such as ketamine. Using databases such as Pubmed, Scopus and Google Scholar, the articles were filtered using inclusion and exclusion criteria. Discussion: Research reveals that these medications offer a promising alternative for refractory patients, contributing to a rapid and positive response compared to traditional antidepressants. Conclusions: Dissociative anesthetics represent a viable option in the therapy of depression, especially in contexts where conventional treatments have failed, highlighting the need for specialized training in these drugs due to the need for follow-up and adequate monitoring in the patient due to the adverse effects of its administration, in addition to its availability in mental health clinics.