Efecto del ácido hipocloroso como alterativa terapéutica en el control de la población de Malassezia pachydermatis en caninos con procesos dermatológicos

Abstract

The objective of this investigation was to determine the effect of hypochlorous acid as a therapeutic alternative in the control of the population of Malassezia pachydermatis in canines with dermatological processes. The study was carried out in the clinics and veterinary centers of the Cevallos canton with the participation of 36 canines with dermatological lesions and signs suggestive of Malassezia. These underwent a superficial cytology examination with Diff-Quick staining in which their overgrowth was confirmed, presenting more than two yeasts on average of ten random visualization fields with an immersion lens of 100 magnification, with a general average of 13 yeasts per field. The 36 canines were divided into two treatments, each with 18 canines. The control group (T0) underwent two daily cleanings with 2% chlorhexidine, while the research group (T1) underwent two daily cleanings with 0.5% hypochlorous acid, lasting 20 days for both groups. The effect of each treatment was evaluated by culture on Sabouraud dextrose agar, with the count of colony-forming units before and after treatment. Obtaining significant differences in both the control group (T0) and the research group (T1), with a reduction of 74.11% and 50.47% respectively. At the end of the treatment, negative cases were observed in both groups, with a count of less than 70 colony-forming units. No statistically significant differences were observed between the treatments, which shows that hypochlorous acid has the same effect as chlorhexidine. Its effectiveness in the control and reduction of yeasts was concluded, and it can be used in dermatological processes with secondary presentation of Malassezia pachyderamatis.