Nefritis lúpica: actualización sobre el manejo deltratamiento a propósito de un caso

Abstract

Lupus Nephritis is derived from Systemic Lupus Erythematosus, an autoimmune disease, whose chronicity dates back a long time under study, the same diseasecauses significant damage within the human body and much more when the person does not receive timely and adequate treatment. It is interesting to be able to determine the mechanisms by which the disease is produced as such and therefore, asin many diseases, a detailed anamnesis must be carried out, considering, among so many options, the appropriate treatment for a person considered as a world individually. It is reported that different medical specialties must be involved in the study of this disease, such as Nephrology, Internal Medicine, Pharmacology, among others. It is more prevalent in women than in men, having a ratio of 9:1 in current data worldwide. In the case of the black and Latin American and Asian race, it is said that it begins at very early ages. It is described that kidney involvement is a serious complication, being responsible for 70 to 80% of patients and that it can induce severe kidney failure within the population in 30 to 70%. It is advisable to take a kidney biopsy, which gives more reliable information on the damage that is taking place in the patient at that moment. Within the treatment it is said that mycophenolate and cyclophosphamide fail in up to 20%, as well as complement inhibitors, anticytokines and in cases stem cell transplantation.