Pronóstico e índice de mortalidad en pacientes VIH positivos infectados por SARS-COV-2

Abstract

Introduction: Currently mortality is linked to diseases caused by COVID-19, so it would be expected to show a high percentage of infections in people with HIV and therefore a high mortality, however, it has been possible to establish through of the information collected, that this population does not have lower levels of contagion, and in case of contagion its mortality rate is equal to that of the population that does not present this disease, for which it is sought to collect current data on the index of mortality and complications of HIV positive patients infected with COVID 19 to try to show if the figures are similar, lower or higher than that of the population without HIV infection. Objective: To determine the degree of severity and mortality rate of HIV patients infected by SARS-COV-2, studying the current scientific evidence on the epidemiology of COVID 19 in the HIV population, analyzing the correlation between the development of severe symptoms of COVID 19 in HIV positive and negative patients. Methodology: This scientific article was carried out based on the scientific literature published in scientific medical databases that have information on the proposed topic, in the Intra Med, PubMed, The Cochrane, SciELO, Elsevier, New England Journal of Medicine databases. , ScienceDirect. 13 scientific articles were used, and 8 systematic reviews published within a range of two years old. Development: Due to the high efficacy of current antiretroviral therapies, most people living with HIV are virologically suppressed and often have normal or slightly decreased CD4 cell counts. Mortality in patients with COVID-19 does not depend solely on their comorbidities, since the presence of complications has been established in terms of clinical manifestations and the management of patients with this disease. Mortality in patients diagnosed with COVID-19 and HIV positive has been able to carry out a series of investigations that allow determining a relationship between the information collected. Discussion: The main relationship between COVID-19 disease and HIV patients is based on the fact that the presentation of clinical manifestations and complications in the analyzed studies do not vary from HIV positive or HIV negative people, despite this it has been possible to establish certain characteristics that can determine slight changes in this presentation due to the belief that patients with HIV generally have a higher risk of serious illness or death, despite this it has not been possible to determine the existence of characteristics directly related to mortality in patients with these two diseases. Conclusion: Mortality in patients diagnosed with COVID-19 and HIV is a subject of study, which has not been able to establish a clear relationship between mortality due to COVID 19 disease in HIV-positive patients and negative patients.