Ciencias de la Salud

URI permanente para esta comunidadhttp://repositorio.uta.edu.ec/handle/123456789/813

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Tema: search.filters.subject.VAGINOSIS BACTERIANA

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    Item type:Ítem,
    MICROBIOTA FECAL EN EL TRATAMIENTO DE LA VAGINITIS BACTERIANA RECURRENTE. REVISIÓN BIBLIOGRÁFICA
    (2025-10-16)
    Jijón Calero, Alexandra Elizabeth
    ;
    Belalcázar Sánchez, Yajaira Monserrath
    ;
    Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Medicina
    Introduction. Recurrent Bacterial Vaginosis (BV) is a common disorder in women of reproductive age, characterized by an imbalance in the vaginal microbiota, with a decrease in lactobacilli and an increase in pathogens such as Gardnerella vaginalis, which has a high recurrence rate and resistance to conventional treatments. Vaginal dysbiosis makes antibiotic treatment difficult, which has prompted the exploration of therapeutic alternatives such as fecal microbiota transplantation (FMT). Objective. To evaluate the effectiveness and safety of FMT in the treatment of recurrent BV. Methodology. Analysis of eight previous clinical studies and systematic reviews using the PRISMA methodology. Results. FMT may be a promising option for restoring vaginal microbial balance, reducing disease recurrences, and improving the quality of life of affected women. Conclusion. Despite positive preliminary results, further research is needed to confirm its effectiveness and ensure its safety before its widespread implementation in clinical practice.
  • Miniatura
    Item type:Ítem,
    RELACIÓN ENTRE LA MICROBIOTA VAGINAL Y LAS INFECCIONES VAGINALES DE MUJERES EN EDAD FÉRTIL
    (2025-10-16)
    Gavilanes Saenz, Brandon Stalin
    ;
    Belalcázar Sánchez Yajaira Monserrath
    ;
    Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Medicina
    Objective: To determine the relationship between vaginal microbiota and vaginal infections in women of childbearing age. Methodology: A systematic documentary review was conducted using scientific databases (PubMed, Dialnet, Google Scholar, SciELO, and Elsevier), selecting articles published between 2020 and 2024. The search was carried out using specific keywords combined with Boolean operators, including both original research and review articles in Spanish or English. Results: Lactobacillus was identified as comprising 70–90% of the healthy vaginal microbiota, maintaining a pH between 3.5 and 4.5 through specific biochemical mechanisms. Bacterial vaginosis emerged as the most prevalent infection (8–51%), followed by vulvovaginal candidiasis (with a lifetime incidence of 70–75%). Vaginal dysbiosis, characterized by the loss of Lactobacillus dominance, facilitates pathogen colonization, establishing a negative feedback loop. Combined therapeutic interventions (antimicrobials and probiotics) showed microbial balance restoration rates of 61.5% at six weeks. Conclusion: There is a bidirectional relationship between the vaginal microbiota and infections, where microbial imbalance predisposes women to infections that, in turn, perpetuate dysbiosis. This cycle is significantly influenced by hormonal factors, particularly estrogen levels, suggesting the need for comprehensiv e therapeutic approaches that consider both pathogen elimination and restoration of the protective microbiota.