Tesis Medicina Veterinaria
Permanent URI for this collectionhttp://repositorio.uta.edu.ec/handle/123456789/36415
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Item Evaluación del ácido hipocloroso como alternativa terapéutica en otitis bacteriana en perros(2023-09) Ayala Calderón, Bryan Alexander; Rosero Peñaherrera, Marco OswaldoThe aim of the present research was to evaluate the effect of hypochlorous acid as a therapeutic alternative in bacterial otitis in dogs, as this is a disease that affects numerous patients, characterized by inflammation of the ear canal and having a diverse etiology. A treatment of 0.05% hypochlorous acid (HC1O) was applied and compared with 1% chlorhexidine in 23 dogs with confirmed bacterial otitis through bacterial cultures, identifying five types of bacteria, with Coagulase-negative Staphylococci (CoNS) being the predominant bacteria, present in more than half of the study subjects. The dogs were divided into two groups, with 12 patients treated with 0.05% HC1O (T1) and 11 with 1% chlorhexidine (T2). Both groups underwent twice-daily ear cleanings for 14 consecutive days. The therapeutic effect of both products was assessed by comparing the results of samples taken before (day 0), during (day 7), and after (day 14) treatment using colony-forming unit (CFU) counts. At the end of the experiment it was obtained that from the total number of bacteria with which the experiment started, there was a 94% decrease in the number of CFU for T1, confirming that for bacterial otitis HC1O works very well as a therapeutic agent to treat bacterial otitis in dogs. As well as comparing the results of T1 and T2, it is confirmed that there is no significant difference between using HC1O at 0.05% or chlorhexidine at 1% since both treatments are equally effective.