Tesis Medicina Veterinaria

Permanent URI for this collectionhttp://repositorio.uta.edu.ec/handle/123456789/36415

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Efecto de la infusión continua de dexmedetomidina sobre la concentración alveolar mínima (CAM) de sevoflurano y eficiencia anestésica en ovariohisterectomía en conejos (Oryctolagus cuniculus)
(2024-08) Chisag Caiza, Gissela Fernanda; Lozada Ortiz, Jenny Piedad
The purpose of this research was to evaluate the effect of continuous infusion of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane and anesthetic efficiency in ovariohysterectomy in rabbits (Oryctolagus cuniculus). Twenty-four clinically healthy 7-month-old female rabbits with an-ASA I and weighing 1.8-3 kg were used. These patients were subjected to a 6-hour fast of solids and 1-hour of liquids prior to the intervention. A completely randomized design with three treatments (two experimental) and a control treatment was applied. The animals were divided by treatments with 8 animals each, that is, T1=8 rabbits, T2=8 rabbits and T3=8 rabbits. In treatment T1, an anesthetic protocol based on ketamine (15mg/kg), midazolam (0.2mg/kg) for premedication was administered intramuscularly (IM), while propofol (2mg/kg) was used intravenously (IV) for induction, In maintenance, sevoflurane was used according to the patient's requirement, at an initial CAM of 3.7% accompanied by a constant rate infusion (CRI), at a dose of 3.5 ug/kg/h of dexmedetomidine. In the second treatment the same anesthetic protocol was used with ketamine (15mg/kg), midazolam (0.2mg/kg) for intramuscular (IM) premedication, propofol (2mg/kg) was used intravenously (IV) for induction, and sevoflurane was used for maintenance according to the patient's requirement, in an initial CAM of 3.7% accompanied by a continuous infusion CRI at a dose of 5 ug/kg/h of dexmedetomidine. In the control treatment T3 the continuous infusion was not applied and a continuous drip of 0.9% sodium chloride was administered applying the same anesthetic protocol mentioned above. The physiological parameters to be evaluated were heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure, mean arterial blood pressure, oxygen saturation, and sevoflurane CAM assessment. By means of an analysis of variance, the best result obtained was with the T2 treatment with an CRI at a dose of 5 ug/kg/h of dexmedetomidine, which does not present significant differences in most of the parameters, keeping them stable; however, a reduction of the CAM at 1.34% of sevoflurane was observed.
Evaluación de los cambios en la calidad seminal de conejos de la raza neozelandés (Oryctolagus cuniculus) de 6 meses, 1 año y 2 años de edad
(2024-08) Molina Chicaiza, Daniela Mishell; Aragadvay Yungan, Ramon Gonzalo
The present investigation focuses on the evaluation of changes in semen quality in New Zealand breed rabbits (Oryctolagus cuniculus) of 6 months, 1 year and 2 years of age. The main objective of the study is to analyze how age affects semen quality parameters in this specific breed. For this purpose, weekly fresh semen collections were performed using an artificial vagina and a female dummy, evaluating both macroscopic and microscopic semen parameters. Analyses included volume, color, motility, sperm consistency, sperm morphology and appearance of fresh semen. The results showed that 1-year-old rabbits presented better semen quality in terms of vitality and concentration, with a lower amount of sperm abnormalities compared to 6-month-old and 2-year-old rabbits. It was determined that age is a significant factor in semen quality in New Zealand breed rabbits. In addition, it is emphasized that dietary supplementation and collection technique do not significantly alter the parameters evaluated, as long as adequate conditions are maintained during the process.
Evaluación de los índices reproductivos de cruzamientos comerciales en conejos (Oryctolagus cuniculus)
(2024-08) Guachi Quishpe, Jonathan Javier; Lozada Salcedo, Euclides Efraín
The objective of this research was to evaluate the reproductive indices of commercial crosses in rabbits (Oryctolagus cuniculus). The experiment used 24 female rabbits of three different breeds: New Zealand (NZ), Butterfly Giant (GM) and Flemish Giant (GFL), as well as two New Zealand (NZ) males. All animals were within specific age ranges of 6 to 7 months and weight of 400 to 500 g. For the statistical analysis, a “Completely Randomized Design” (DCA) was used due to the homogeneity of the treatments. The response variables were subjected to an analysis of variance (ANOVA) to identify significant differences. For the comparison of means, the Duncan statistical test was used (p≤ 0.05). All statistical analyzes were carried out using Infostat software, version 2019. Maternal ability was evaluated by collecting all the reproductive indices of the crosses, in order to determine whether the does have outstanding or poor maternal ability. The results showed that the NZ x GFL cross had the highest number of live-born kits (7.00), unlike the two treatments that had lower results such as NZ x NZ (6.38) and NZ x GM (6.00). ,35). Furthermore, the NZ x GFL cross showed lower mortality at birth at 1%, compared to 4% for NZ x NZ and 6% for NZ x GM. In terms of weaning mortality, NZ x GFL also had the lowest rate at 5%, followed by NZ x NZ at 10% and NZ x GM at 12%. Additionally, the number of weaned kits was higher in NZ x GFL (6.63) and NZ x GM (5.75), compared to NZ x NZ (5.5). On the other hand, weaning weight was significantly higher in NZ x GM 286.75 g than in NZ x GFL 283.13 g and NZ x NZ 262.13 g. In conclusion, the NZ x GFL cross optimizes the survival and growth of young rabbits, demonstrating superior maternal ability and being recommended as a cross to improve reproductive rates.