REVISIÓN BIBLIOGRÁFICA: PREVALENCIA DE LA INFECCIÓN POR HELICOBACTER PYLORI DROGORESISTENTE

Abstract

Introduction: Helicobacter pylori infection is a disease of worldwide distribution, it is known that half of the population is a carrier of the bacterium. The importance of studying the prevalence of drug resistance of Helicobacter pylori is to know the resistance patterns of antibiotics used in the treatment of the infection in order to investigate the modifications necessary for the correct eradication of the disease. Objective: To describe the prevalence of drug resistance in Helicobacter pylori infection in the last 10 years. Methodology: This literature review is based on a retrospective study, search and analysis of studies, essays and meta-analyses published in the databases: PubMed, Scielo, Science Direct, Web of Science, Mediagraphic, Elsevier, Springer. Results: The prevalence of drug resistance depends on geographical location. The treatment lines used for the eradication of Helicobacter pylori infection have increased their resistance rates in the last 10 years. In addition, a higher prevalence of resistance is observed in previously treated individuals than in patients who never received eradication treatment. Conclusions: The studies found in this literature review have limitations, which means that the prevalence differs according to the regions and the lines of treatment used. In the studies analyzed, the prevalence of drug resistance against metronidazole and clarithromycin is the highest compared to other antibiotics and has maintained a constant growth