Esteatosis hepática no alcohólica y su relación con diabetes mellitus tipo 2. Revisión bibliográfica

Abstract

Non-alcoholic steatosis of the liver (NAFLD) is considered a generally asymptomatic disease, characterized by the accumulation of ectopic fat at the hepatocyte level, without toxic alcohol consumption, the global prevalence is estimated at 24%, up to 80%. % of diabetic patients present NAFLD, various pathophysiological mechanisms not yet well established related to both peripheral and hepatic insulin resistance (IR), promotes steatosis and the development of NAFLD, liver biopsy is the gold standard study for diagnosis, the treatment is based instead on a lifestyle based on diet and exercise, further research is still required for the use of drugs that improve insulin resistance. For this review, a search was carried out in different databases such as: Pubmed, SciencieDirect, Medline, Elsevier, Google Scholar, Scielo and New England Journal of Medicine from 2017 to 2022.