Determinación de Niveles de la Enzima Lactato Deshidrogenasa y su Relación con los Trastornos Hipertensivos Durante el Embarazo

Abstract

This researching project was done with the goal of determining the levels of the enzyme lactate dehydrogenase and relates with the hypertensive disorders during pregnancy in patients attending to the Gynecology Area of the Hospital Basic Latacunga Clinic and patients attending to the Maternity Area of the General provincial hospital Latacunga. It has been made an association study of variables in which was attended by 81 women of 15 years and older, in gestation period of 3 to 9 months or puerperal state and hads problem of gestational hypertension. They were performed to patients having blood drawn for the respective laboratory tests in compliance with the proposed objective.

As a result of the determination of the levels of lactate dehydrogenase enzyme from the 81 patients it was obtained that 38% of patients have normal values of 222 U/L to 450 U/L LDH HUMAN, while 35% of the values are decreased less than 222 U/L and 27% of the values are elevated higher than 234 U/L. It is observed that patients with high levels of LDH are related to the presence of a hypertensive disorder during pregnancy especially preeclampsia, accompanied by clinical data of interest along with other laboratory tests.

The hypothesis testing was performed using the CHI-SQUARE X2 test statistic, and comparing the result of Chi2 calculated that equals 109.383016 with Chi2 Tabular its value corresponds to 5.9915; it can be seen that the Chi2 Calculated is greater than Chi2 Tabular; therefore the null hypothesis is rejected and the alternative hypothesis that tells us that "The levels of lactate dehydrogenase enzyme are elevated in hypertensive disorders during pregnancy" is accepted.