Browsing by Author "Oñate Guachón, Rocío Abigail"

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Diabetes mellitus tipo 2 como complicación en pacientes postcovid 19
(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2023-07-03) Oñate Guachón, Rocío Abigail; Acosta Gavilanez, Roberto Iván
Diabetes mellitus as a consequence of SARS-CoV 2 infection is a rare entity that has been presented in recent times as a com plication at the pancreatic level, the mechanisms for its production are directly related to the damage of the gland at both exocrine and endocrine level, the main feature is manifested when the angiotensin - converting enzyme 2 (ACE2) initially located at the pulmonary level was identified as the major functional receptor for SARS-CoV2, However, it is now known that ACE2 is present not only at the pulmonary level, but also at the heart, kidney, esophagus, ileum, colon and finally at the pancreas level, thanks to research conducted directly with SARS-CoV2 positive SARS patients. The purpose of this article is to raise awareness of SARS -CoV-2 as a possible trigger and enhancer of diabetes mellitus in postcovida patients. There is a bidirectional relationship between COVID-19 and diabetes mellitus. Patients with diabetes increase the risk of developing complications by contracting the infection, however COVID -19 can also act as a diabetogenic agent by binding to ACE2 present in pancreatic beta cells causing irreversible damage, another factor considered is the inflammatory state that causes COVID-19, These inflammatory states are the cause of generating hyperglycemic states and insulin resistance, which is why the continuous monitoring of glucose in patients who have suffered infections by the Covid 19 v irus will be essential for the prevention of diabetes in the future.