Browsing by Author "Arcos Cuamacas Micaela Elizabeth"

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    Determinación de niveles de anticuerpos antirrábicos post-vacunales en caninos de diferentes edades
    (2025-02) Arcos Cuamacas Micaela Elizabeth; Villavicencio Villavicencio Blanca Jeaneth
    Canine distemper is a highly contagious viral disease that mainly affects carnivores. For a better understanding of the immune response and the effectiveness of vaccination against this disease, a detailed investigation was conducted at Dr. Pets Veterinary Clinic over a period of two months. The study focused on evaluating post-vaccinal antibody levels in puppies from 2 to 3 months of age, which were selected under specific criteria: good health status confirmed by clinical examination, normal physiological constants, and absence of previous vaccinations. The methodology employed included immunofluorescence tests to measure the immune response generated after vaccination. The findings of the investigation were significant and revealing. A remarkable increase in IgG antibody titers was observed, from a mean of 1:10 in the antevaccination measurement to 1:120 in the post-vaccination measurement, evidencing an effective immune response. In contrast, IgM antibodies showed a different behavior, with a slight reduction from 1:38.5 to 1:32. This decrease is consistent with the normal dynamics of the immune response, where IgM, although the first antibodies to appear, are characterized by a short half-life.