Importancia del dímero D en pacientes Covid-19

Abstract

The coronavirus disease 2019 (COVID-19) has generated a great impact worldwide due to its high morbidity and mortality. It produces numerous clinical pictures, but respiratory complications are the main factor for admission of patients to intensive care units. However, there are other clinical manifestations related to hypercoagulability that have been colligated with an increased probability of mortality and hospitalization in these patients. D -Dimer can beused as a prognostic factor for severity or deterioration in patients with COVID -19. Materials and methods: We conducted a literature review, qualitative approach, non- experimental type that emphasized the importance of D -Dimer as a biomarker used in patients with COVID-19 from different articles between 2020 to 2022. Results: Considerable bibliographic sources agree that D-Dimer as a plasma biomarker sensitively reflects the coagulation state of the organism and presents a positive correlation with the cruelty of this disease. Discussion: DDimer is one of the most significant biomarkers asa prognostic factor of criticality or deterioration of the state of individuals with COVID-19 and its value determines behaviours in anticoagulation and hospitalization. Conclusions and recommendations : D-Dimer is a predictor of severity, including mortality, in individuals with COVID-19. Although, the evidence emphasizes that D - Dimer has a high sensitivity in the presence of thromboembolism, its specificity is low because it increases in other circumstances. A greater number of studies are recommended in order to evaluate different factors that can confirm the validity of this biomarker.