Factores de no adherencia terapeutica al tarv(terapia anti retroviral) en pacientes con sindrome de inmunodeficiencia adquirida (VIH/sida)

Abstract

Introduction: HIV is the acquired immunodeficiency virus for which there is still no cure, but whose most successful treatment is ART, which has achieved a significant reduction in morbidity and mortality from this cause when administered properly and in a timely manner. Objective: To analyse the factors of nonadherence

to ART (Anti-Retroviral Therapy) in patients with Acquired Immunodeficiency Syndrome (HIV/AIDS). Methods: A systematic review of scientific articles and publications directly related to the subject of study was carried out, in the period 2015-2020, in databases such as: VHL, LILACS, PUBMED, MEDIGRAPHIC, MEDLINE, ELSEVIER, SCIELO, through descriptors such as: "HIV", "AIDS", "ASSOCIATED FACTORS", "NON-ADHERENCE", "TREATMENT". Results: The articles selected for the development of the systematic review were 41, which were selected from a total of 240 reported in the different databases in the period October-November 2020. Most of the articles agree that the main factors for the lack of adherence to antiretroviral treatment in patients infected with HIV/AIDS are personal and health-related. Conclusions: The factors for non-adherence to ART are varied as they depend on intrinsic and extrinsic elements but they must be addressed because non-adherence to treatment can trigger repercussions such as: a greater number of opportunistic diseases and complications related to the start of treatment, a lesser response to antiretroviral treatment, low life expectancy and a greater risk of the spread of the disease.