Klebsiella pneumoniae resistente a los carbapenémicos en infecciones intrahospitalarias, una revisión en Latinoamérica

Abstract

The aim of this study was to determine the presence of carbapenem-resistant Klebsiella pneumoniae in nosocomial infections in Latin America, and to analyze its frequency and tendency in Latin American. Methods: This study is a literature review, it was carried out through exhaustive research in different databases Analytical and descriptive cohort studies, meta-analysis and some clinical trials related to the presence of nosocomial infections caused by carbapenem-resistant K. pneumoniae and the genes responsible for this resistance were included. Results: Twenty-two articles were selected from different databases from Latin American countries; In addition, the percentages of resistance to carbapenemics in K. pneumoniae in these countries and its trend before and during the COVID-19 pandemic were identified. Conclusions Resistance to carbapenemics in K. pneumoniae was determined as a public health problem in Latin America, considered as a limiting factor in the treatment of patients with infections caused by this Enterobacteral. In addition, it was identified that KPC is the main gene responsible for carbapenem resistance.