Correlación clínica entre cáncer gástrico y grupos sanguíneos

Abstract

Introduction: Gastric Cancer (GC) is a neoplasm in which malignant cells grow in the lining of the stomach. Age, diet, stomach condition and other factors contribute to the risk of developing this type of cancer. GC symptoms include indigestion and discomfort or pain. The objective of this study was focused on demonstrating that there is a clinical correlation between GC and blood groups by combining data collected between 2018 - 2022. Materials and Method: A descriptive, non-experimental documentary method was carried out through a reference review of different scientific articles and studies related to the subject from 2018 to 2022. Results: According to various bibliographic sources, it was established that within the ABO Blood Group System, especially A, they were related to the appearance of GC alongside other risk factors. Discussion: After the reference review, most of the authors agreed that blood group A was mostly related to GC. While other correlated risk factors were identified as environmental such as diet and the influence of H. pylori infection. The ABO gene, the only one to control the ABO blood group system, codes for a glycosyltransferase that modifies the carbohydrate content of antigens in red blood cells. This could be related to the development of GC. Conclusions and Recommendations: This study demonstrated the relationship between CG and blood groups, especially blood group A, unlike patients with blood group O, they usually develop peptic ulcers. It allows follow-up of patients with this characteristic, which leads to developing new study methods and implementin g early diagnosis and timely treatment.