Cambios bioquímicos en la edad adulta tardía de una población de la sierra ecuatoriana

Abstract

The impact of biochemical changes in the elderly has the same factor in common since they present alterations in their old age and those described are seen in glucose metabolism as: morphological and functional. The First ones are associated with an increase in visceral fat, fatty tissue infiltration and lower beta cell mass, the second ones are observed in increased production of adipokines, inflammatory factors, as well as increased insulin resistance and diabetes. Changes in lipid metabolism fluctuate and alter lipoproteins, cholesterol, and triglycerides; It can be evidenced when measuring these serum analytes, thus causing dyslipidemia. The research is focused on identifying the main biochemical changes in glucose and lipid profile analyzes (cholesterol, triglycerides, HDL and LDL) in a population of 89 older adults from the province of Tungurahua, Ecuador, through a study with a descriptive design, transverse, field. Using the Minitab version 18.1 software, it was possible to determine that with a 95% reliable interval there are no changes in the analytes of glucose, total cholesterol, HDL and LDL. On the other hand, with a reliable interval of 95% of 100%, 14% may have a value above 150mg/dL in the triglyceride analyte in both men and women. The percentage of patients with a tendency to suffer from biochemical changes is relatively low in our research, which is why the physical activity carried out by the study patients has been determined as a protective factor given their way of working, despite this hypertriglyceridemia stands out by 14%. Likewise, a high percentage of geriatric patients state that they have developed diabetes in 64% (n = 57), but show little knowledge of the disease, since they say they suffer from it, but it is not reflected in the laboratory results that they present such a disease.