“Determinación del ancho de la curva de distribución Eritrocitaria en pacientes con dmt2 y su relación con el daño renal”

Abstract

The present research project aimed to determine the Width of the Erythrocyte Distribution Curve (RDW) in patients with type 2 diabetes mellitus and its relation to renal damage. The RDW is an index to evaluate the variation of red blood cell volume. Recently, RDW was significantly associated with increased mortality in patients with Diabetes Mellitus, changes in RDW are also associated with the production of some inflammatory cytokines, and oxidative stress play an important role in the pathogenesis of damage renal. Regarding the methodology, the work approach was qualitative, applying field research, laboratory, and a level of longitudinal analytical research. We included 38 patients with DMT2 with a mean age of 60.39 ± 14.93 years of age. Each patient underwent two blood biometric and blood chemistry analyzes and correlated the values obtained. Based on the results of calculating the estimated glomerular filtration rate (eGFR) in the study population, it was possible to divide into 5 categories: 12 patients with normal or elevated glomerular filtration rate (GFR), 9 with Damage Renal and mild decrease in GFR, 1 with mild-moderate GFR, 2 with moderate GFR, and 14 with renal failure. Multiple logistic regression indicated that RDW (p <0.001) was an independent risk factor for kidney damage in mellitus diabetes type 2.