Determinación de Perfil Tiroideo y su relación con el Anticuerpo Antiperoxidasa Tiroidea en pacientes con Vitíligo

Abstract

The determination of peroxidase antibodies and thyroid profile has been suggested in patients with Vitiligo knowing that there are other factors that can affect the levels of the hormones of the thyroid profile as well as, those of peroxidase in blood antibodies. The relationship that exists between these parameters and the Vitiligo is still dispute the few studies that exist in the Ecuador. For the study included 40 patients men/women aged 6 to 78 who were diagnosed with Vitiligo, the mean age of men was 42 years old, while in women it was 35-year-old. The samples entered the clinical laboratory, they were analyzed using the technique of Electroquioluminicencia TSH: sandwich, T3: competition, T4: competition and the results analyzed by ANOVA system. The age and gender did not differ significantly in the results of the samples analyzed. Mean ± standard deviation of serum TSH concentrations were 6.61 ± 5.04 UI and anti-TPO Autoantibodies were 139,05 ± 238,59 UI. The correlation between the two (TSH / Pearson = 17.17 TPO) was statistically significant (p = 0.0001), 19 patients (90.5%) of the positive anti-TPO had hypothyroidism. In the same way, only two (9.5%) were eutiroideos.