Cuantificación de Linfocitos T Cd4 en Pacientes con Vih y su Relación con el Desarrollo de Enfermedades Oportunistas en Hospitalización del Área de Infectología del Hospital Carlos Andrade Marín (Hcam)

Abstract

The main purpose of this project is the quantification of CD4 T lymphocytes in patients with acquired immunodeficiency syndrome (HIV) and relate it with the development of opportunistic diseases. After reviewing the medical records of patients diagnosed with HIV who are hospitalized in the area of Infectious Diseases in Carlos Andrade Marin HOSPITAL IESS from Quito, the population who met the inclusion criteria were selected. Patients were invited to join the project after socializing the purpose there of, and after signing the informed consent, was established to work with 95 patients between 18 and 64 years. The CD4 T lymphocyte count was performed by flow cytometry. After tabulating the results obtained from the analysis of biological samples, it was concluded that the average CD4 lymphocyte count was 296.326 ± 205.8802. The 73.6% (n = 70) of the patients presented opportunistic diseases with a count <400 cel./ mm3. Of this percentage, cerebral toxoplasmosis (n = 19/95, 20%) had the highest prevalence with a count <100 cells / mm3.