Efectos clínicos que produce el gluten sobre la población que sufre enfermedad celíaca

Abstract

Celiac disease is defined as a chronic immune-mediated enteropathy that affects the small intestine in genetically predisposed people. This research aimed to determine the clinical effects of gluten on the population suffering from celiac disease, its pathogenesis, laboratory tests that may show alterations, and serological tests that permit its detection. This study used a documentary approach to describe and gather relevant information from published articles related to the study variables. It focused on the fact that this disease is often significantly underdiagnosed, and it is frequently asymptomatic or shows mild symptoms. This causes inadequate treatment which potentially results in other health problems and even death in the long term. In conclusion, it is necessary to perform relevant serological tests in order to prevent the disease from progressing along with other complications. It is also important to mention that currently, the anti-tTG IgA test is conducted as the initial step in laboratory diagnosis.