“Síndrome de Stevens Johnson por consumo de Aines”

Abstract

Stevens-Johnson syndrome (SSJ) is named after Albert Mason Stevens and Frank Chambliss Johnson, American pediatricians.

SJS is a blistering disease, due to epidermal detachment and erosion.

The three major causes of SJS / NET are reactions to drugs, infections, and cancer. NSAIDs ranked third with 24.6% of all patients

The present case describes a 40 - year - old female patient, from the city of Ambato (Tungurahua - Ecuador), who 48 hours ago presented flushing and facial edema as well as ampullary lesions on the lips, with apparent eosinophil consumption (etoricoxib) 120 Mg vo so he comes to emergency where they administer antihistamine, corticoid and H2 receptor antagonist, partially giving the picture and sent home, returns to the emergency room 24 hours referring to dermal lesions in facial region, anterior thorax, and inner face of Thighs, represented in a 20% of total body surface after which it is entered to the service of Internal Medicine. The second day of hospitalization shows the presence of hyperchromic macules, eroded plaques, scabs and blisters and a positive nykolsky sign is seen, oral corticosteroid is started, it is evaluated by the Department of Dernatology and Immunology, completing a study with a previous chest skin biopsy Which reports skin and appendages with detachment above the basal layer, focus of spongiosis, focus of epithelial ulceration and superficial inflammatory polymorphonuclear infiltrate, biopsy shows compatibility with exanthemic reaction by drugs.

On the third day, lesions persist, such as blisters, scabs and hyperpigmentation macules occupying 15% of the total body surface area. On his fourth day of hospitalization patient in better conditions, crusts and blisters in the process of resolution. It is decided to discharge the 4th day of hospitalization.