Determinación de la Vitamina D y los Factores Predisponentes para desencadenar Osteoporosis en mujeres Post-Menopáusicas

Abstract

Osteoporosis is a disease characterized by the global nature deterioration of bone micro architecture of human body. Given the importance of health, one of my goals was to find the relationship between the values of vitamin D with osteoporosis and be able to identify the factors that may contribute to the onset of the disease, from the post-menopause. For the implementation of this project it was compulsory to apply a survey in order to identify the main predisposing factors, and determine the values of vitamin D by electrochemiluminescence immunoassay test (ECLIA). A descriptive, quantitative and cross-sectional study, where 40 women were analyzed samples of postmenopausal immunoassay by applying the method for determining electrochemiluminescence levels 25.hidroxivitamina D. The results indicate that the main predisposing factors are vitamin D intake low, the sedentary lifestyle, high intake of alcohol and caffeine as principal. According to serum levels of 25-hydroxyvitamin D, results indicate that 37.5% of vitamin D levels were within normal, 47.5% showed a moderate deficient level, while 15% present deficient levels. According to the study applied to the patients who had deficient levels, it was discovered that most of them had osteopenia and osteoporosis and indicated the deficient intake of vitamin D. The serum concentration of vitamin D is not a parameter that can be used directly to diagnose osteoporosis, because there is a single test that serves to it as is the bone densitometry. However, the levels of vitamin D together with calcium, are very important for the doctor to collectively predict with clinical osteoporosis patient. We talk about osteopenia or osteoporosis because the patient with osteopenia or osteoporosis usually has low or deficient 25.hydroxyvitamin D. The importance of evaluating vitamin D in postmenopausal patients with osteoporosis is a pillar of great importance in the treatment accompanied with calcium recommended by the doctor. The methodology was done in the clinical laboratory of the General Hospital of Latacunga, there were 40 post-menopausal patients, and through verification of bone densitometry, it was determined that there were women apparently healthy, or had osteopenia or osteoporosis, and with the analysis of vitamin D we concluded that in most postmenopausal patients vitamin D is low.