“Actividad antifúngica de los extractos de plantas croton lechleri y maytenus laevis en cepas de candida albicans atcc 10231”

Abstract

Candida albicans is a type of fungy mainly known as having an important opportunistic behavior, and because of its increased incidence and treatment, it has become highly resistant to drugs. For this reason, the goal of this research is to evaluate the active substances from the flowering such as Croton lechleri and Maytenus laevis gotten from the country widespread rainforest and used mainly by the Shuar tribe in Ecuador. It was performed a maceration and a lyophilization of Croton lechleri (latex cortex) y Maytenus laevis (cortex), next to prepare the ethanol-based extracts. The antifungal activity was inferred by the agar distribution technique (sabouraud) placing into the bowls in the growing environment 100uL y 200uL from the concentration extracts 1/10. It was observed the inhibition haloes appearance in the growing yeast next to the Croton lechleri, but no appearance of haloes next to Maytenus laevis. To ensure that the results are consistent, it was performed the sensibility breeding test, where it was evident again the growing inhibition of the yeast next to the Croton lechleri extract to concentrations of 10mg/mL y 20mg/mL, with no positive results for Maytenus laevis. The statistical data analysis was done using the Graph Pad Prism 6 software, performing a variance analysis (ANOVA) and T de Student.