Determinación de Blee Producidas por Klebsiella Pneumoniae y su Relacion con la Resistencia a los Antimicrobianos

Abstract

The presence of therapeutic failure in Enterobacteriaceae infections has conducted this study to the mechanisms of resistance of these microorganisms and inactivating enzymes of the beta-lactam antibiotics (betalactamase)-producing bacteria are proven. Within the Group of beta-lactamase-producing bacteria are the so-called beta-lactamases of spread spectrum or ESBL able achieve bacterial resistance to cephalosporins of 3rd and 4ta generation, which is a serious problem in the treatment of infections in hospitalized patients in the Latacunga Hospital and by the importance of this health issue, proposed identify the presence of these microorganisms and their behavior in vitro to antimicrobial agents we use. The ss-lactam antimicrobials are the most used drugs for the treatment of bacterial infections, both at the level of the community as a hospital. The broad spectrum, low toxicity and the strongly bactericide on the majority of microorganisms are some of the causes of its extensive use. Hospitalized patients urine cultures were performed to determine the presence of these bacteria. 66.7% of the crops studied presented infection by Klebsiella pnemoniae and BLEE producing strains.