Determinación de Colinesterasa en Pacientes Sometidos A Anestesia General

Abstract

This research took place in Unidad Oncologica Solca Tungurahua and in San Gabriel Clinical Laboratory. Its target was to demonstrate if the enzyme Plasmatic Cholinesterase has action against bromuro de rocuronio which is a muscle blocker used in general anesthesia and surgical reactions that may occur as prolonged muscle lock and apneas.

I worked with a population of 48 patients selected through inclusion and exclusion criteria, from 30 to 70 years of age between men and women whose surgeries were previously scheduled.

Statistical data and aspects that were necessary for this research were obtained through medical records of patients.

For taking the first sample it was necessary to verified that patients had the criteria of this research also the progress of each surgery until the end in order to garner the second and final sample. Quantitative results were obtained, 39 women and 9 men were the number of Population undergoing to general Surgery with established diagnosis and control of the disease.

In conclusion the values of postsurgical cholinesterase presented a variation but not outside the normal range. So 81% of total population had normal values of cholinesterase 10% high values and 4% low values.