Ciencias de la Salud
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Item Hipoglucemia en pacientes diabéticos en tratamiento con glibenclamida(Universidad Técnica de Ambato/Facultad de Ciencias de la Salud/Carrera de Medicina, 2022-10-24) Rodríguez Meza, José Andrés; Morales Solís, Jorge MarceloGlibenclamide is a potent hypoglycemic agent that helps to maintain lower serum glucose levels in diabetics, which may confer a higher risk of hypoglycemia as an acute complication than with the use of other oral hypoglycemic agents, such as metformin. The purpose of this review is to collect and to summarize updated information on the mechanism of hypoglycemia in diabetic patients during treatment with glibenclamide, the risk factors that predispose diabetic patients to suffer hypoglycemia, and the frequency with which hypoglycemia may occur as adverse reaction during treatment of diabetes. Its mechanism of action consists of the inhibition of ATP-dependent potassium channels in the beta cells of the pancreas, where it stimulates the secretion of insulin by these cells. As its function is independent of serum glucose levels, hypoglycemia frequently manifests as an adverse effect of its administration. The effect of the drug is enhanced in cases such as patients with long-standing diabetes or comorbidities like kidney failure, the use of high doses or the use of other drugs that enhance its effect. Even though the use of glibenclamide as a cause of hypoglycemia is predicted to be underestimated, it is predicted that approximately 1 in 5 patients treated with this drug may experience hypoglycemia during the diabetes therapy. This factor directly influences the quality of life of the diabetic patient, as well as their adherence to hypoglycemic treatment, who chooses to abandon this medication or request a change in the scheme and the drug of choice for their therapy.Item Diabetes Mellitus Tipo 2 + Tumor en Páncreas/ Adenocarcinoma de Páncreas(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Enfermería, 2016-06-01) Guevara Espejo, Luz Milagros; .Gavilanes Fray, Verónica Del Pilar Lic. EspSeveral studies show a clear association between diabetes mellitus and the development of pancreas adenocarcinoma because its complications are not uncommon and they have to be treated in the best way possible keeping a metabolic equilibrium. This study case has to do with an elderly male patient with a pancreatic cancer associated to diabetes due to the fact that this gland produces juices that help assimilate food and the hormones that propitiate the regulation of glucose levels in the blood. Most of the information was gathered from the clinical history of the patient. This information, which was necessary for the analysis, was collected with the patient’s and the family’s cooperation and was used as a reference point. The nursing assistance is based on the scientific method which allow us to provide care in a rational, logical, and systematic manner. This allows us as future nursing professionals make independent decisions in order to achieve objectives deriving from our assistance which will improve the patient’s health state. Each day, the impact of the assistance to diabetic peopleis more noticeable, as well as the evidence that education is essential on its therapeutic approach. That’s why, with this case, we attempt to increase the level of trust on the daily work of the nursing professional. This will turn into a more efficient service for people with this chronic condition.