Relación del perfil lipídico y transaminasas en una esteatohepatitis no alcohólica.

Abstract

Non-alcoholic steatohepatitis is a disease that mainly affects people who eat a diet rich in saturated fat. It is characterized by the absence of symptoms; therefore, it is not possible to predict it. It is based on the accumulation of fat in the hepatocytes, which is called steatosis that progresses until it reaches fibrosis. This is the main characteristic of the presence of NASH in these patients. There are factors that lead to this pathology, mainly insulin resistance, type II diabetes mellitus, obesity, hyperlipidemia. Patients with cardiovascular diseases are also prone to getting NASH. Studies carried out in different countries worldwide establish that in Latin America there is a prevalence of 31% of this pathology in people. In our country, hepatic cirrhosis ranks seventh as a cause of mortality in patients with NASH. The determination of non-alcoholic steatohepatitis at the laboratory level is carried out by evaluating the lipid profile, as well as the TGO and TGP transaminases. However, to confirm it, a liver biopsy is performed, which allows us to see the morphology of the NASH. The degree of damage in which the hepatocyte is found, is considered a very common test but not repetitive due to the risks involved in its performance