Evaluación de la acción del ácido hipocloroso como alternativa terapéutica en enteritis bacteriana neonatal bovina

Abstract

The present investigation had the objective of evaluating the action of hypochlorous acid (HClO) as a treatment of bovine neonatal bacterial enteritis. The study was carried out in 16 crossbred male calves aged between 1 and 2 weeks, which were located in a place of high epidemiological risk and contracted bacterial enteritis. 4 treatment groups were formed with 4 calves respectively. In three groups, 3 doses of HClO were used; T1: 0.5 ml/kg, T2: 1 ml/kg, T3: 1.5 ml/kg which were administered orally twice a day, the other group was T0: ceftiofur at a dose of 2.2 ml /kg every 12 hours; the time of the application of the treatments was 5 days. The variables analyzed. Degree of affectation of enteritis classified from 0 to 5 where there were no statistical differences in the treatments. Degree of diarrhea classified from 0 to 4 where T0, T2 and T3 were different from T1. Stool frequency that recorded the number of stools of the animal per day where there were no statistical differences in the treatments. Vital signs; temperature, heart rate and respiratory rate are taken and there were no statistical differences in the treatments except for heart rate where T1 was different from T3. Bacterial load was assessed on the CFU of E. coli where there were no statistical differences in the treatments. Leukogram, the values of the analyte’s leucites, neutrophils, lymphocytes and monocytes were recorded in which there were no statistical differences in the treatments. By demonstrating that HClO has the same effect as antibiotic therapy, it was concluded that HClO can be used as a treatment for neonatal bacterial enteritis.