Efectos del uso de ivermectina en humanos durante la pandemia de COVID-19

Abstract

The ivermectin has used as an alternative treatment for COVID-19 due to preclinical evidence of its efficacy treating virus like dengue, yellow fever, VIH 1, and SARS –COV- 2. Some research has demonstrated that its administration in positive patients with Covid- 19, it helps to mitigated symptoms, reduced mortality, and reduce recovery time, showing efficacy to reduce the viral charge, anti-inflammatory effects, and antiviral, however, its administration has had secondary effects related to dose administered. In that way, this investigation is based in a bibliographic review Its objective to identify the effects of the ivermectin use in humans thought the COVID-19 pandemic. The results show that the most common effects are, fatigue, diarrhea, nausea, headache, abdominal pain, and fever in those patients whose received the safe therapeutic dose of 200 μg/kg in humans, however, high doses can cause convulsions, liver disease, hypotension, edema, tachycardia, and skin ulcer, by consequence of overdoses, however, the effects are not permanent.