“Valores séricos de anticuerpos (igg) antitetánicos y su relación con el desarrollo de preeclampsia en mujeres embarazadas que cursan el tercer trimestre de gestación”

Abstract

The study of serum anti-tetanus IgG values is a new, innovative and very important research for the country because there are no previous studies on this subject. This project was carried out between the Ambato General Teaching Hospital, the Technical University of Ambato and the San Francisco University of Quito, whose main objective was to analyze the serum values of anti-tetanus IgG antibodies and establish whether the preeclamptic patients are fully immunized according to the scheme of the Ministry of Public Health of Ecuador. The type of research was exploratory because there are not enough previous studies in the country, it is also cross-sectional descriptive because the data of the demographic variables collected in a given period of time were analyzed on a predefined population or sample, since the objective was to verify the hypothesis proposed and to verify if there are protective titers of antitetanic IgG in pregnant women with preeclampsia. The study population was 73 preeclamptic patients who were in the third trimester of pregnancy, this sample was calculated by applying the sample size formula to obtain a proportion in a finite or known population. The results obtained in the present investigation through the ELISA test in the laboratory and Pearson's Chi-square Frequency Descriptive and Chi-square statistical estimators allowed us to know the most representative demographic variables in which preeclampsia and equals are more frequent. To corroborate that the titers of the antitetanic IgG are directly proportional to the time of placement of the last dose of the dT vaccine. It was concluded that the preeclamptic patients studied have anti-tetanus IgG titers in high concentrations with a mean of 86.31 IU, this being a high value and in turn protective against the infectious agent producing tetanus and confirming that patients are immunized..